- Title
- Alzheimer’s Disease Detection Using Deep Learning on Neuroimaging: A Systematic Review
- Creator
- Alsubaie, Mohammed G.; Luo, Suhuai; Shaukat, Kamran
- Relation
- Machine Learning and Knowledge Extraction Vol. 6, Issue 1, p. 464-505
- Publisher Link
- http://dx.doi.org/10.3390/make6010024
- Publisher
- MDPI AG
- Resource Type
- journal article
- Date
- 2024
- Description
- Alzheimer’s disease (AD) is a pressing global issue, demanding effective diagnostic approaches. This systematic review surveys the recent literature (2018 onwards) to illuminate the current landscape of AD detection via deep learning. Focusing on neuroimaging, this study explores single- and multi-modality investigations, delving into biomarkers, features, and preprocessing techniques. Various deep models, including convolutional neural networks (CNNs), recurrent neural networks (RNNs), and generative models, are evaluated for their AD detection performance. Challenges such as limited datasets and training procedures persist. Emphasis is placed on the need to differentiate AD from similar brain patterns, necessitating discriminative feature representations. This review highlights deep learning’s potential and limitations in AD detection, underscoring dataset importance. Future directions involve benchmark platform development for streamlined comparisons. In conclusion, while deep learning holds promise for accurate AD detection, refining models and methods is crucial to tackle challenges and enhance diagnostic precision.
- Subject
- Alzheimer's disease; AD detection; convolutional neural network; recurrent neural network; graph neural network; autoencoders
- Identifier
- http://hdl.handle.net/1959.13/1502663
- Identifier
- uon:55259
- Identifier
- ISSN:2504-4990
- Rights
- © 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
- Language
- eng
- Full Text
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